Pamidronate Disodium For Injection

Pamidronate Disodium for Injection[Pharmacology]Pamidronate is structurally classified as a bisphosphonate. Both in vitro studies and animal studies show that it strongly inhibitsHydroxyapatite dissolution and the activity of osteoclasts, thus exhibiting notable effect in inhibiting bone resorption.[Pharmacodynamics]Pamidronate is distributed mainly in the bone, liver, spleen and trachea cartilage, etc. It is eliminated from the blood circulation rapidly. 51%Of the drug is eliminated in the original form from urine 4 hours after intravenous injection. The elimination of the drug through urine isOf the bi-phase characteristic, ¦Áand¦Â phase half life time (T1/2) is 1.6 and 27.2 hours respectively. The drug can remain in the boneTissue for up to 300 days.[Indications]- Tumor-induced hypercalcemia.- Bone pain induced by osteolytic bone metastasis. product offered by Shenzhen Neptunus Interlong Biotech Co., Ltd.